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There are no regulated clinical information pertaining to sexual disorder with paroxetine use. There are numerous records of priapism linked with paroxetine use. In cases in which outcome was reported, all clients totally recuperated. [Ref]

Cardiovascular negative effects have often consisted of pulsation (2 % to 3 %), vasodilation (2 % to 4 %), hypertension (2 %), and also tachycardia (consisting of torsade de pointes). Bradycardia, hematoma, hypotension, postural hypotension, syncope, angioedema, angina pectoris, nodal arrhythmia, atrial fibrillation, bundle branch block, cerebral anemia, cerebrovascular accident, coronary infarction, heart block, reduced heart outcome, myocardial infarct, myocardial ischemia, phlebitis, supraventricular extrasystoles, thrombophlebitis, apoplexy, varicose vein, supraventricular tachycardia, vascular headache, vasculitic syndromes (consisting of Henoch-Schonlein purpura), ventricular extrasystoles, and also ventricular fibrillation have actually additionally been stated. [Ref]

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Paroxetine- induced hyponatremia could be more typical in elderly female clients and those which are volume depleted or are receiving concomitant diuretic therapy. [Ref]

The endcrine system negative effects have actually consisted of diabetic issues mellitus, goiter, hyperthyroidism, thyroiditis, and also hypothyroidism. Hyperprolactinemia, hyponatremia, and also the disorder of unacceptable antidiuretic bodily hormone (SIADH) are significantly being connected with careful serotonin reuptake inhibitors including paroxetine. An instance of intense dangerous hyponatremia in a patient obtaining paroxetine has been reported. [Ref]

Hematologic negative side effects have included anemia, leukopenia, lymphadenopathy, purpura, abnormal erythrocytes, basophilia, raised bleeding time, eosinophilia, hypochromic anemia, iron insufficiency anemia, leukocytosis, lymphedema, unusual lymphocytes, lymphocytosis, microcytic anemia, monocytosis, normocytic anemia, thrombocythemia, thrombocytopenia, hemolytic anemia, as well as events associated with damaged hematopoiesis (consisting of aplastic anemia, pancytopenia, bone bottom aplasia, and agranulocytosis). Numerous instances have actually also been reported suggesting that paroxetine may cause blood loss in clients with normal bleeding times, platelet counts, prothrombin times, and partial thromboplastin times. [Ref]

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